Target：Sox-8/9/17/18

Gene Name：SOX8/9/17/18

Protein Name：Transcription factor SOX-8/9/17/18

Human Gene Id：30812/6662/64321/54345

Human Swiss Prot No：P57073/P48436/Q9H6I2/P35713

Mouse Gene Id：20681/20682/20671/20672

Immunogen：The antiserum was produced against synthesized peptide derived from human SOX8/9/17/18. AA range:116-165

Specificity：Sox-8/9/17/18 Polyclonal Antibody detects endogenous levels of Sox-8/9/17/18 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SOX8;Transcription factor SOX-8;SOX9;Transcription factor SOX-9;SOX17;Transcription factor SOX-17;SOX18;Transcription factor SOX-18

Observed Band(KD)：47kD

Background：SRY-box 8(SOX8) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq, Jul 2008],

Function：function:May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.,similarity:Contains 1 HMG box DNA-binding domain.,

Subcellular Location：Nucleus .

Expression： Brain,Spleen,