Target：HRK

Fields：Apoptosis

Gene Name：HRK BID3

Protein Name：Activator of apoptosis harakiri (BH3-interacting domain-containing protein 3) (Neuronal death protein DP5)

Human Gene Id：8739

Human Swiss Prot No：O00198

Mouse Swiss Prot No：P62816

Rat Swiss Prot No：P62817

Immunogen：Synthesized peptide derived from part region of human protein AA range: 1-50

Specificity：HRK Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：10kD

Background：harakiri, BCL2 interacting protein(HRK) Homo sapiens This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],

Function：domain:The BH3 motif is required for the induction of cell death.,function:Activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L).,

Subcellular Location：Membrane; Single-pass membrane protein. Mitochondrion.