Target：HLX1

Gene Name：HLX

Protein Name：H2.0-like homeobox protein

Human Gene Id：3142

Human Swiss Prot No：Q14774

Mouse Gene Id：15284

Mouse Swiss Prot No：Q61670

Rat Gene Id：364069

Rat Swiss Prot No：A0JPN1

Immunogen：The antiserum was produced against synthesized peptide derived from human HLX1. AA range:321-370

Specificity：HLX1 Polyclonal Antibody detects endogenous levels of HLX1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HLX;HLX1;H2.0-like homeobox protein;Homeobox protein HB24;Homeobox protein HLX1

Observed Band(KD)：75kD

Background：function:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.,sequence caution:Translation N-terminally extended.,similarity:Belongs to the H2.0 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.,

Function：function:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.,sequence caution:Translation N-terminally extended.,similarity:Belongs to the H2.0 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.,

Subcellular Location：Nucleus .

Expression：Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.