Target：Sox-17

Fields：Wnt signaling pathway

Gene Name：SOX17

Protein Name：Transcription factor SOX-17

Human Gene Id：64321

Human Swiss Prot No：Q9H6I2

Mouse Gene Id：20671

Mouse Swiss Prot No：Q61473

Immunogen：Synthesized peptide derived from Sox-17 . at AA range: 90-170

Specificity：Sox-17 Polyclonal Antibody detects endogenous levels of Sox-17 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SOX17;Transcription factor SOX-17

Observed Band(KD)：44kD

Background： This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008],

Function：function:Probable transcriptional activator in the premeiotic germ cells. It binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum.,

Subcellular Location：Nucleus .

Expression：Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum.