Target：Sos 2
Fields：EGFR tyrosine kinase inhibitor resistance;Endocrine resistance;MAPK signaling pathway;ErbB signaling pathway;Ras signaling pathway;Chemokine signaling pathway;FoxO signaling pathway;Phospholipase D signaling pathway;mTOR signaling pathway;PI3K-Akt signaling pathway;Focal adhesion;Gap junction;JAK-STAT signaling pathway;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;B cell receptor signaling pathway;Fc epsilon RI signaling pathway;Thermogenesis;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;Insulin signaling pathway;GnRH signaling pathway;Estrogen signaling pathway;Prolactin signaling pathway;Relaxin signaling pathway;Growth hormone synthesis, secretion and action;Alcoholism;Hepatitis C;Hepatitis B;Human cytomegalovirus infection;Human papillomavirus infection;Pathways in cancer;Proteoglycans in cancer;MicroRNAs in cancer;Chemical carcinogenesis - receptor activation;Che
Gene Name：SOS2
Protein Name：Son of sevenless homolog 2
Human Gene Id：6655
Human Swiss Prot No：Q07890
Mouse Swiss Prot No：Q02384
Immunogen：The antiserum was produced against synthesized peptide derived from human SOS2. AA range:631-680
Specificity：Sos 2 Polyclonal Antibody detects endogenous levels of Sos 2 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：SOS2;Son of sevenless homolog 2;SOS-2
Observed Band(KD)：150kD
Background： This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016],
Function：function:Promotes the exchange of Ras-bound GDP by GTP.,online information:Son of sevenless entry,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GEF domain.,
Subcellular Location：intracellular,cytosol,
Expression： Brain,Placenta,
