Target：SORC1

Gene Name：SORCS1 SORCS

Protein Name：VPS10 domain-containing receptor SorCS1 (hSorCS)

Human Gene Id：114815

Human Swiss Prot No：Q8WY21

Mouse Swiss Prot No：Q9JLC4

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SORC1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：128kD

Background： This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Function：similarity:Contains 1 PKD domain.,similarity:Contains 5 BNR repeats.,tissue specificity:Detected in fetal and infant brain and in fetal retina.,

Subcellular Location：Membrane; Single-pass type I membrane protein.

Expression：Detected in fetal and infant brain and in fetal retina.