Target：SNX4

Fields：Endocytosis

Gene Name：SNX4

Protein Name：Sorting nexin-4

Human Gene Id：8723

Human Swiss Prot No：O95219

Mouse Gene Id：69150

Mouse Swiss Prot No：Q91YJ2

Immunogen：The antiserum was produced against synthesized peptide derived from human SNX4. AA range:191-240

Specificity：SNX4 Polyclonal Antibody detects endogenous levels of SNX4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SNX4;Sorting nexin-4

Observed Band(KD)：60kD

Background： This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012],

Function：function:May be involved in several stages of intracellular trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,

Subcellular Location：Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Also detected on a juxtanuclear endocytic recycling compartment (ERC). .

Expression： Liver,Skin,