Target:SMAGP
Gene Name:SMAGP
Protein Name:Small cell adhesion glycoprotein (Small transmembrane and glycosylated protein)
Human Gene Id:57228
Human Swiss Prot No:Q0VAQ4
Mouse Swiss Prot No:Q99KC7
Rat Swiss Prot No:Q7TPF1
Immunogen:Synthesized peptide derived from human protein . at AA range: 30-110
Specificity:SMAGP Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):10kD
Background:function:May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.,PTM:O-glycosylated. The O-glycan is modified with sialic acid residues.,similarity:Belongs to the SMAGP family.,subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors.,tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).,
Function:function:May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.,PTM:O-glycosylated. The O-glycan is modified with sialic acid residues.,similarity:Belongs to the SMAGP family.,subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors.,tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).,
Subcellular Location:Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle membrane ; Single-pass type III membrane protein . Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913). Detected on cytoplasmic membranes in undifferentiated tumors (PubMed:15986429). .
Expression:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).