Target：Slit3

Fields：Axon guidance

Gene Name：SLIT3

Protein Name：Slit homolog 3 protein

Human Gene Id：6586

Human Swiss Prot No：O75094

Mouse Gene Id：20564

Mouse Swiss Prot No：Q9WVB4

Rat Gene Id：83467

Rat Swiss Prot No：O88280

Immunogen：Synthesized peptide derived from the Internal region of human Slit3.

Specificity：Slit3 Polyclonal Antibody detects endogenous levels of Slit3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLIT3;KIAA0814;MEGF5;SLIL2;Slit homolog 3 protein;Slit-3;Multiple epidermal growth factor-like domains protein 5;Multiple EGF-like domains protein 5

Molecular Weight(Da)：168kD

Background： The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

Function：function:May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.,sequence caution:Intron retention.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 23 LRR (leucine-rich) repeats.,similarity:Contains 9 EGF-like domains.,tissue specificity:Predominantly expressed in thyroid.,

Subcellular Location：Secreted .

Expression：Predominantly expressed in thyroid.