Target：SKI

Gene Name：SKI

Protein Name：Ski oncogene (Proto-oncogene c-Ski)

Human Gene Id：6497

Human Swiss Prot No：P12755

Mouse Swiss Prot No：Q60698

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SKI Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：80kD

Background：SKI proto-oncogene(SKI) Homo sapiens This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation. [provided by RefSeq, Oct 2009],

Function：function:May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage.,similarity:Belongs to the SKI family.,subunit:Interacts with SMAD2, SMAD3 and SMAD4. Interacts with HIPK2. Part of a complex with HIPK2 and SMAD1/2/3.,

Subcellular Location：Nucleus.