Target：SEMA3F

Fields：Axon guidance

Gene Name：SEMA3F

Protein Name：Semaphorin-3F

Human Gene Id：6405

Human Swiss Prot No：Q13275

Mouse Gene Id：20350

Mouse Swiss Prot No：O88632

Immunogen：The antiserum was produced against synthesized peptide derived from human SEMA3F. AA range:734-783

Specificity：SEMA3F Polyclonal Antibody detects endogenous levels of SEMA3F protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SEMA3F;Semaphorin-3F;Sema III/F;Semaphorin IV;Sema IV

Observed Band(KD)：88kD

Background： This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],

Function：developmental stage:Detected as early as embryonic day 10.,function:May play a role in cell motility and cell adhesion.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Sema domain.,tissue specificity:Expressed abundantly but differentially in a variety of neural and nonneural tissues. There is high expression in mammary gland, kidney, fetal brain, and lung and lower expression in heart and liver.,

Subcellular Location：Secreted .

Expression：Expressed abundantly but differentially in a variety of neural and nonneural tissues. There is high expression in mammary gland, kidney, fetal brain, and lung and lower expression in heart and liver.