Target：SEM6A

Fields：Axon guidance

Gene Name：SEMA6A KIAA1368 SEMAQ

Protein Name：Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)

Human Gene Id：57556

Human Swiss Prot No：Q9H2E6

Mouse Swiss Prot No：O35464

Immunogen：Synthesized peptide derived from human protein . at AA range: 430-510

Specificity：SEM6A Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：113kD

Background： The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011],

Function：function:Can act as repulsive axon guidance cues. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,subunit:Active as a homodimer or oligomer. Interacts with EVL.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression： Brain,Hypothalamus,Placenta,