Target：SEC62

Fields：Protein export;Protein processing in endoplasmic reticulum

Gene Name：SEC62 TLOC1

Protein Name：Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1)

Human Gene Id：7095

Human Swiss Prot No：Q99442

Mouse Swiss Prot No：Q8BU14

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SEC62 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：51kD

Background： The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008],

Function：function:Required for preprotein translocation.,similarity:Belongs to the SEC62 family.,subunit:Part of a complex that contains SEC61, SEC62 and SEC63. Interacts with SEC61B.,

Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Expression： Epithelium,Liver,Mammary gland,Prostate,