Target：SCGF

Gene Name：CLEC11A

Protein Name：C-type lectin domain family 11 member A

Human Gene Id：6320

Human Swiss Prot No：Q9Y240

Mouse Gene Id：20256

Mouse Swiss Prot No：O88200

Rat Gene Id：29313

Rat Swiss Prot No：O88201

Immunogen：The antiserum was produced against synthesized peptide derived from the N-terminal region of human CLEC11A. AA range:1-50

Specificity：SCGF Polyclonal Antibody detects endogenous levels of SCGF protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CLEC11A;CLECSF3;LSLCL;SCGF;C-type lectin domain family 11 member A;C-type lectin superfamily member 3;Lymphocyte secreted C-type lectin;Stem cell growth factor;p47

Observed Band(KD)：30kD

Background： This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008],

Function：developmental stage:In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.,function:Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.,online information:Stem cell growth factor,PTM:O-glycosylated. Probably sulfated on the O-glycans.,similarity:Contains 1 C-type lectin domain.,tissue specificity:Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.,

Subcellular Location：Cytoplasm . Secreted .

Expression：Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.