Target:SCCA1/2
Fields:Amoebiasis
Gene Name:SERPINB3/SERPINB4
Protein Name:Serpin B3/Serpin B4
Human Gene Id:6317
Human Swiss Prot No:P29508
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINB3/4. AA range:111-160
Specificity:SCCA1/2 Polyclonal Antibody detects endogenous levels of SCCA1/2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:SERPINB3;SCCA;SCCA1;Serpin B3;Protein T4-A;Squamous cell carcinoma antigen 1;SCCA-1
Observed Band(KD):45kD
Background:developmental stage:Its expression is closely related to cellular differentiation in both normal and malignant squamous cells.,function:May act as a protease inhibitor to modulate the host immune response against tumor cells.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level.,tissue specificity:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).,
Function:developmental stage:Its expression is closely related to cellular differentiation in both normal and malignant squamous cells.,function:May act as a protease inhibitor to modulate the host immune response against tumor cells.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level.,tissue specificity:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).,
Subcellular Location:Cytoplasm . Seems to also be secreted in plasma by cancerous cells but at a low level.
Expression:Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).