Target：APOA2

Fields：PPAR signaling pathway;Cholesterol metabolism

Gene Name：APOA2

Protein Name：Apolipoprotein A-II (Apo-AII) (ApoA-II) (Apolipoprotein A2) [Cleaved into: Truncated apolipoprotein A-II (Apolipoprotein A-II(1-76))]

Human Gene Id：336

Human Swiss Prot No：P02652

Mouse Swiss Prot No：P09813

Rat Swiss Prot No：P04638

Immunogen：Synthesized peptide derived from part region of human protein AA range: 1-50

Specificity：APOA2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：11kD

Background： This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008],

Function：function:May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.,mass spectrometry: PubMed:12562854,mass spectrometry:Cysteinylated ApoA-II PubMed:12562854,mass spectrometry:Heterodimer with apolipoprotein A-II(1-76) PubMed:12562854,mass spectrometry:Homodimer PubMed:12562854,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the apolipoprotein A2 family.,subunit:Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP.,tissue specificity:Plasma; synthesized in the liver and intestine.,

Subcellular Location：Secreted .

Expression：Plasma; synthesized in the liver and intestine.