Target：ACOT4

Fields：Fatty acid elongation;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Ovarian steroidogenesis

Gene Name：ACOT4

Protein Name：Acyl-coenzyme A thioesterase 4

Human Gene Id：122970

Human Swiss Prot No：Q8N9L9

Mouse Swiss Prot No：Q8BWN8

Immunogen：The antiserum was produced against synthesized peptide derived from human ACOT4. AA range:361-410

Specificity：ACOT4 Polyclonal Antibody detects endogenous levels of ACOT4 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ACOT4;PTE2B;PTEIB;Acyl-coenzyme A thioesterase 4;Acyl-CoA thioesterase 4;PTE-2b;Peroxisomal acyl coenzyme A thioester hydrolase Ib;Peroxisomal long-chain acyl-CoA thioesterase Ib;PTE-Ib

Observed Band(KD)：48kD

Background：catalytic activity:Palmitoyl-CoA + H(2)O = CoA + palmitate.,function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.,similarity:Belongs to the C/M/P thioester hydrolase family.,

Function：catalytic activity:Palmitoyl-CoA + H(2)O = CoA + palmitate.,function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.,similarity:Belongs to the C/M/P thioester hydrolase family.,

Subcellular Location：Peroxisome .

Expression：Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle.