Target：AKAP 14

Gene Name：AKAP14

Protein Name：A-kinase anchor protein 14

Human Gene Id：158798

Human Swiss Prot No：Q86UN6

Immunogen：The antiserum was produced against synthesized peptide derived from human AKAP14. AA range:1-50

Specificity：AKAP 14 Polyclonal Antibody detects endogenous levels of AKAP 14 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：AKAP14;AKAP28;A-kinase anchor protein 14;AKAP-14;A-kinase anchor protein 28 kDa;AKAP 28;Protein kinase A-anchoring protein 14;PRKA14

Observed Band(KD)：23kD

Background： The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Function：caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Binds to type II regulatory subunits of protein kinase A and anchors/targets them.,subunit:Binds to type II regulatory subunits (RII).,tissue specificity:Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.,

Subcellular Location：Cytoplasm .

Expression：Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.