Target：S6A12

Fields：Synaptic vesicle cycle;GABAergic synapse

Gene Name：SLC6A12

Protein Name：Sodium- and chloride-dependent betaine transporter (BGT-1) (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12)

Human Gene Id：6539

Human Swiss Prot No：P48065

Mouse Swiss Prot No：P31651

Rat Swiss Prot No：P48056

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：S6A12 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：67kD

Background：function:Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subunit:Interacts with LIN7C.,tissue specificity:Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.,

Function：function:Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subunit:Interacts with LIN7C.,tissue specificity:Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.,

Subcellular Location：Membrane; Multi-pass membrane protein.

Expression：Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.