Target：S39A5

Fields：Alzheimer disease;Parkinson disease

Gene Name：SLC39A5 ZIP5

Protein Name：Zinc transporter ZIP5 (Solute carrier family 39 member 5) (Zrt- and Irt-like protein 5) (ZIP-5)

Human Gene Id：283375

Human Swiss Prot No：Q6ZMH5

Mouse Swiss Prot No：Q9D856

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：S39A5 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：59kD

Background： The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],

Function：function:May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status.,PTM:Glycosylated.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,tissue specificity:Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.,

Subcellular Location：Basolateral cell membrane ; Multi-pass membrane protein .

Expression：Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.