Target：S-100A3

Gene Name：S100A3

Protein Name：Protein S100-A3

Human Gene Id：6274

Human Swiss Prot No：P33764

Mouse Gene Id：20197

Mouse Swiss Prot No：P62818

Rat Gene Id：114216

Rat Swiss Prot No：P62819

Immunogen：The antiserum was produced against synthesized peptide derived from human S100A3. AA range:26-75

Specificity：S-100A3 Polyclonal Antibody detects endogenous levels of S-100A3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：S100A3;S100E;Protein S100-A3;Protein S-100E;S100 calcium-binding protein A3

Molecular Weight(Da)：12kD

Observed Band(KD)：22kD

Background：S100 calcium binding protein A3(S100A3) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008],

Function：function:Binds both calcium and zinc. Probably binds 2 zinc ions per molecule. May be involved in calcium-dependent cuticle cell differentiation and hair shaft formation.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Skin specific.,

Subcellular Location：Cytoplasm .

Expression：Skin specific, specifically expressed at the inner endocuticle of hair fibers.