Target：Hepassocin

Gene Name：FGL1

Protein Name：Fibrinogen-like protein 1

Human Gene Id：2267

Human Swiss Prot No：Q08830

Mouse Gene Id：234199

Mouse Swiss Prot No：Q71KU9

Rat Swiss Prot No：Q5M8C6

Immunogen：Synthesized peptide derived from the Internal region of human Hepassocin.

Specificity：Hepassocin Polyclonal Antibody detects endogenous levels of Hepassocin protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FGL1;HFREP1;Fibrinogen-like protein 1;HP-041;Hepassocin;Hepatocyte-derived fibrinogen-related protein 1;HFREP-1;Liver fibrinogen-related protein 1;LFIRE-1

Observed Band(KD)：36kD

Background：fibrinogen like 1(FGL1) Homo sapiens Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008],

Function：function:Has hepatocyte mitogenic activity.,similarity:Contains 1 fibrinogen C-terminal domain.,subunit:Homodimer.,tissue specificity:Liver specific.,

Subcellular Location：Secreted . Secreted in the blood plasma. .

Expression：Under normal conditions, liver-specific.