Target：HEN1/2

Gene Name：HEN1/HEN2

Protein Name：Helix-loop-helix protein 1

Human Gene Id：4807/4808

Human Swiss Prot No：Q02575/Q02577

Mouse Gene Id：18071/18072

Immunogen：The antiserum was produced against synthesized peptide derived from human HEN1/2. AA range:41-90

Specificity：HEN1/2 Polyclonal Antibody detects endogenous levels of HEN1/2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NHLH1;BHLHA35;HEN1;Helix-loop-helix protein 1;HEN-1;Class A basic helix-loop-helix protein 35;bHLHa35;Nescient helix loop helix 1;NSCL-1;NHLH2;BHLHA34;HEN2;KIAA0490;Helix-loop-helix protein 2;HEN-2;Class A basic helix-loop-he

Observed Band(KD)：19kD

Background： The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002],

Function：function:May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,

Subcellular Location：Nucleus .

Expression： Brain,Eye,