Target：HBAZ

Gene Name：HBZ HBZ2

Protein Name：Hemoglobin subunit zeta (HBAZ) (Hemoglobin zeta chain) (Zeta-globin)

Human Gene Id：3050

Human Swiss Prot No：P02008

Mouse Swiss Prot No：P06467

Immunogen：Synthesized peptide derived from human protein . at AA range: 10-90

Specificity：HBAZ Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：15kD

Background： Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'. [provided by RefSeq, Nov 2009],

Function：function:The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin, synthesized primarily in the yolk sac.,similarity:Belongs to the globin family.,subunit:Heterotetramer of two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1; two zeta chains and two gamma chains in hemoglobin Portland-1.,tissue specificity:Red blood cells.,

Subcellular Location：hemoglobin complex,extracellular exosome,

Expression：Detected in fetal erythrocytes (at protein level).