Target：Gγ 5

Fields：Ras signaling pathway;Chemokine signaling pathway;PI3K-Akt signaling pathway;Apelin signaling pathway;Circadian entrainment;Retrograde endocannabinoid signaling;Glutamatergic synapse;Cholinergic synapse;Serotonergic synapse;GABAergic synapse;Dopaminergic synapse;Relaxin signaling pathway;Morphine addiction;Alcoholism;Human cytomegalovirus infection;Kaposi sarcoma-associated herpesvirus infection;Human immunodeficiency virus 1 infection;Pathways in cancer

Gene Name：GNG5

Protein Name：Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5

Human Gene Id：2787

Human Swiss Prot No：P63218

Mouse Gene Id：1.00044e+008

Mouse Swiss Prot No：Q80SZ7

Rat Gene Id：1.0036e+008

Rat Swiss Prot No：P63219

Immunogen：The antiserum was produced against synthesized peptide derived from human GNG5. AA range:10-59

Specificity：Gγ 5 Polyclonal Antibody detects endogenous levels of Gγ 5 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GNG5;GNGT5;Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5

Molecular Weight(Da)：7kD

Background：G protein subunit gamma 5(GNG5) Homo sapiens G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 [PubMed 3113327]; summary by Ahmad et al., 1995) [PubMed 7606925].[supplied by OMIM, Nov 2010],

Function：function:Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.,similarity:Belongs to the G protein gamma family.,subunit:G proteins are composed of 3 units, alpha, beta and gamma.,

Subcellular Location：Cell membrane ; Lipid-anchor ; Cytoplasmic side .

Expression： Brain,Platelet,Umbilical cord blood,