Target：GUF1

Gene Name：GUF1

Protein Name：Translation factor GUF1 mitochondrial

Human Gene Id：60558

Human Swiss Prot No：Q8N442

Mouse Swiss Prot No：Q8C3X4

Immunogen：The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470

Specificity：GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GUF1;Translation factor GUF1; mitochondrial;Elongation factor 4 homolog;EF-4;GTPase GUF1;Ribosomal back-translocase

Molecular Weight(Da)：74kD

Background： This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],

Function：similarity:Belongs to the GTP-binding elongation factor family. LepA subfamily.,

Subcellular Location：Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .

Expression： Brain,Colon,Lung adenocarcinoma,Teratocarcinoma,