Target:GPSN2
Fields:Fatty acid elongation;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Fatty acid metabolism
Gene Name:TECR
Protein Name:Trans-2,3-enoyl-CoA reductase
Human Gene Id:9524
Human Swiss Prot No:Q9NZ01
Mouse Gene Id:106529
Mouse Swiss Prot No:Q9CY27
Rat Gene Id:191576
Rat Swiss Prot No:Q64232
Immunogen:The antiserum was produced against synthesized peptide derived from human GPSN2. AA range:259-308
Specificity:GPSN2 Polyclonal Antibody detects endogenous levels of GPSN2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TECR;GPSN2;SC2;Trans-2;3-enoyl-CoA reductase;TER;Synaptic glycoprotein SC2
Molecular Weight(Da):36kD
Background: This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011],
Function:steroid biosynthetic process, steroid metabolic process, lipid biosynthetic process, oxidation reduction,
Subcellular Location:Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Expression:Expressed in most tissues tested. Highly expressed in skeletal muscle.