Target:GPR92
Fields:Rap1 signaling pathway;Phospholipase D signaling pathway;PI3K-Akt signaling pathway;Regulation of actin cytoskeleton;Pathogenic Escherichia coli infection;Pathways in cancer
Gene Name:LPAR5
Protein Name:Lysophosphatidic acid receptor 5
Human Gene Id:57121
Human Swiss Prot No:Q9H1C0
Mouse Swiss Prot No:Q149R9
Immunogen:The antiserum was produced against synthesized peptide derived from human GPR92. AA range:241-290
Specificity:GPR92 Polyclonal Antibody detects endogenous levels of GPR92 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:LPAR5;GPR92;GPR93;Lysophosphatidic acid receptor 5;LPA receptor 5;LPA-5;G-protein coupled receptor 92;G-protein coupled receptor 93
Observed Band(KD):40kD
Background:lysophosphatidic acid receptor 5(LPAR5) Homo sapiens This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008],
Function:function:Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.,
Subcellular Location:Cell membrane; Multi-pass membrane protein.
Expression:Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.