Target：GPR43

Fields：cAMP signaling pathway

Gene Name：FFAR2

Protein Name：Free fatty acid receptor 2

Human Gene Id：2867

Human Swiss Prot No：O15552

Mouse Swiss Prot No：Q8VCK6

Immunogen：The antiserum was produced against synthesized peptide derived from human FFAR2. AA range:271-320

Specificity：GPR43 Polyclonal Antibody detects endogenous levels of GPR43 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FFAR2;GPR43;Free fatty acid receptor 2;G-protein coupled receptor 43

Molecular Weight(Da)：37kD

Background： This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009],

Function：function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Expressed at relatively high levels in peripheral blood leukocytes and, to lesser extent, in spleen.