Target：RTN4R
Gene Name：RTN4R NOGOR UNQ330/PRO526
Protein Name：Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor)
Human Gene Id：65078
Human Swiss Prot No：Q9BZR6
Mouse Swiss Prot No：Q99PI8
Rat Swiss Prot No：Q99M75
Immunogen：Synthesized peptide derived from human protein . at AA range: 270-350
Specificity：RTN4R Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：52kD
Background： This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. [provided by RefSeq, Jul 2008],
Function：function:Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.,online information:Nerve regrowth: nipped by a no-go - Issue 69 of April 2006,similarity:Belongs to the Nogo receptor family.,similarity:Contains 9 LRR (leucine-rich) repeats.,subunit:Homomultimer. Interacts with LINGO1.,tissue specificity:Widespread in the brain but highest levels in the gray matter. Low levels in heart and kidney not expressed in oligodendrocytes (white matter).,
Subcellular Location：Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft . Cell projection, dendrite . Cell projection, axon . Perikaryon . Detected along dendrites and axons, close to synapses, but clearly excluded from synapses. .
Expression：Widespread in the brain but highest levels in the gray matter. Low levels in heart and kidney; not expressed in oligodendrocytes (white matter).
