Target：GPR172A

Gene Name：SLC52A2

Protein Name：Solute carrier family 52 riboflavin transporter member 2

Human Gene Id：79581

Human Swiss Prot No：Q9HAB3

Mouse Swiss Prot No：Q9D8F3

Immunogen：The antiserum was produced against synthesized peptide derived from human PEVR1. AA range:43-92

Specificity：GPR172A Polyclonal Antibody detects endogenous levels of GPR172A protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLC52A2;GPR172A;PAR1;RFT3;Solute carrier family 52; riboflavin transporter, member 2;Porcine endogenous retrovirus A receptor 1;PERV-A receptor 1;Protein GPR172A;Riboflavin transporter 3;hRFT3

Observed Band(KD)：46kD

Background： This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunctio

Function：function:Acts as cell surface receptor for porcine endogenous retrovirus (PERV-A).,similarity:Belongs to the PERVR family.,tissue specificity:Detected in a wide variety of tissues. High expression in testis.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression：Highly expressed in brain, fetal brain and salivary gland. Weakly expressed in other tissues.