Target：GPR17

Gene Name：GPR17

Protein Name：Uracil nucleotide/cysteinyl leukotriene receptor

Human Gene Id：2840

Human Swiss Prot No：Q13304

Mouse Gene Id：574402

Mouse Swiss Prot No：Q6NS65

Rat Gene Id：767613

Rat Swiss Prot No：Q09QM4

Immunogen：The antiserum was produced against synthesized peptide derived from human GPR17. AA range:196-245

Specificity：GPR17 Polyclonal Antibody detects endogenous levels of GPR17 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GPR17;Uracil nucleotide/cysteinyl leukotriene receptor;UDP/CysLT receptor;G-protein coupled receptor 17;P2Y-like receptor;R12

Observed Band(KD)：59kD

Background：function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,

Function：function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.