Target：ABC3C

Fields：Viral life cycle - HIV-1;Human immunodeficiency virus 1 infection

Gene Name：APOBEC3C APOBEC1L PBI

Protein Name：Probable DNA dC->dU-editing enzyme APOBEC-3C (EC 3.5.4.-) (APOBEC1-like) (Phorbolin I)

Human Gene Id：27350

Human Swiss Prot No：Q9NRW3

Immunogen：Synthesized peptide derived from human protein . at AA range: 10-90

Specificity：ABC3C Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：20kD

Background： This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008],

Function：cofactor:Zinc.,function:Unknown. Unable to reduce HIV-1 infectivity in vitro.,miscellaneous:It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,tissue specificity:Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary.,

Subcellular Location：Nucleus . Cytoplasm .

Expression：Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary.