Target:GPR139
Gene Name:GPR139
Protein Name:Probable G-protein coupled receptor 139
Human Gene Id:124274
Human Swiss Prot No:Q6DWJ6
Mouse Gene Id:209776
Mouse Swiss Prot No:Q80UC8
Rat Gene Id:293545
Rat Swiss Prot No:P0C0W8
Immunogen:The antiserum was produced against synthesized peptide derived from human GPR139. AA range:181-230
Specificity:GPR139 Polyclonal Antibody detects endogenous levels of GPR139 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GPR139;GPRG1;PGR3;Probable G-protein coupled receptor 139;G(q)-coupled orphan receptor GPRg1;G-protein-coupled receptor PGR3
Observed Band(KD):40kD
Background: This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Function:function:Orphan receptor. Seems to act through a G(q/11)-mediated pathway.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed almost exclusively in the brain. Detected at very low levels in the peripheral tissues.,
Subcellular Location:Cell membrane; Multi-pass membrane protein.
Expression:Expressed almost exclusively in the brain. Detected at very low levels in the peripheral tissues.