Target：GPR103

Fields：Neuroactive ligand-receptor interaction

Gene Name：QRFPR

Protein Name：Pyroglutamylated RFamide peptide receptor

Human Gene Id：84109

Human Swiss Prot No：Q96P65

Mouse Gene Id：229214

Mouse Swiss Prot No：P83861

Rat Gene Id：310327

Rat Swiss Prot No：P83858

Immunogen：The antiserum was produced against synthesized peptide derived from human GPR103. AA range:271-320

Specificity：GPR103 Polyclonal Antibody detects endogenous levels of GPR103 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：QRFPR;GPR103;Pyroglutamylated RFamide peptide receptor;AQ27;G-protein coupled receptor 103;Orexigenic neuropeptide QRFP receptor;SP9155

Observed Band(KD)：49kD

Background：function:Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed widely in the brain with high levels in the hypothalamus, trigeminal ganglia and vestibular neurons, and moderate levels in the amygdala, cortex, pituitary, hippocampus, thalamus, caudate nucleus and medulla oblongata. In peripheral tissues, expressed at high levels in the retina and at moderate levels in the heart, kidney, testis and thyroid.,

Function：function:Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed widely in the brain with high levels in the hypothalamus, trigeminal ganglia and vestibular neurons, and moderate levels in the amygdala, cortex, pituitary, hippocampus, thalamus, caudate nucleus and medulla oblongata. In peripheral tissues, expressed at high levels in the retina and at moderate levels in the heart, kidney, testis and thyroid.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Expressed widely in the brain with high levels in the hypothalamus, trigeminal ganglia and vestibular neurons, and moderate levels in the amygdala, cortex, pituitary, hippocampus, thalamus, caudate nucleus and medulla oblongata. In peripheral tissues, expressed at high levels in the retina and at moderate levels in the heart, kidney, testis and thyroid.