Target：LRP4

Gene Name：LRP4 KIAA0816 LRP10 MEGF7

Protein Name：Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)

Human Gene Id：4038

Human Swiss Prot No：O75096

Mouse Swiss Prot No：Q8VI56

Rat Swiss Prot No：Q9QYP1

Immunogen：Synthesized peptide derived from human protein . at AA range: 290-370

Specificity：LRP4 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：209kD

Background： This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010],

Function：function:Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes.,similarity:Belongs to the LDLR family.,similarity:Contains 20 LDL-receptor class B repeats.,similarity:Contains 3 EGF-like domains.,similarity:Contains 8 LDL-receptor class A domains.,tissue specificity:Expressed in several regions of the brain.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression：Expressed in bone; present in osteoblasts and osteocytes. No expression is observed in osteoclast. Expressed in several regions of the brain.