Target：CNDD3

Gene Name：NCAPD3 CAPD3 KIAA0056

Protein Name：Condensin-2 complex subunit D3 (Non-SMC condensin II complex subunit D3) (hCAP-D3)

Human Gene Id：23310

Human Swiss Prot No：P42695

Mouse Swiss Prot No：Q6ZQK0

Immunogen：Synthesized peptide derived from part region of human protein. AA range 1-150

Specificity：CNDD3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：164kD

Background：non-SMC condensin II complex subunit D3(NCAPD3) Homo sapiens Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008],

Function：function:Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.,similarity:Contains 4 HEAT repeats.,subunit:Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and 3 non SMC subunits that probably regulate the complex: NCAPH2, NCAPD3 and NCAPG2.,

Subcellular Location：Nucleus .

Expression： Bone marrow,Brain,Epithelium,Eye,Placenta,