Target：CMTM8

Gene Name：CMTM8

Protein Name：CKLF-like MARVEL transmembrane domain-containing protein 8

Human Gene Id：152189

Human Swiss Prot No：Q8IZV2

Mouse Gene Id：70031

Mouse Swiss Prot No：Q9CZR4

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human CMTM8. AA range:101-150

Specificity：CMTM8 Polyclonal Antibody detects endogenous levels of CMTM8 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CMTM8;CKLFSF8;CKLF-like MARVEL transmembrane domain-containing protein 8;Chemokine-like factor superfamily member 8

Observed Band(KD)：20kD

Background： This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],

Function：similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in liver and pancreas.,

Subcellular Location：[Isoform 1]: Membrane; Multi-pass membrane protein.; [Isoform 2]: Cytoplasm. Nucleus.

Expression：Highly expressed in liver and pancreas.