Target：CLN6

Gene Name：CLN6

Protein Name：Ceroid-lipofuscinosis neuronal protein 6

Human Gene Id：54982

Human Swiss Prot No：Q9NWW5

Immunogen：The antiserum was produced against synthesized peptide derived from human CLN6. AA range:221-270

Specificity：CLN6 Polyclonal Antibody detects endogenous levels of CLN6 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：CLN6;Ceroid-lipofuscinosis neuronal protein 6;Protein CLN6

Observed Band(KD)：40kD

Background： This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008],

Function：disease:Defects in CLN6 are the cause of variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL) [MIM:601780].,online information:Neural Ceroid Lipofuscinoses mutation db,

Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein . Endoplasmic reticulum .

Expression： Epithelium,Lung,Urinary bladder,