Target：CLLD7
Gene Name：RCBTB1
Protein Name：RCC1 and BTB domain-containing protein 1
Human Gene Id：55213
Human Swiss Prot No：Q8NDN9
Mouse Gene Id：71330
Mouse Swiss Prot No：Q6NXM2
Immunogen：The antiserum was produced against synthesized peptide derived from human RCBTB1. AA range:251-300
Specificity：CLLD7 Polyclonal Antibody detects endogenous levels of CLLD7 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：RCBTB1;CLLD7;E4.5;RCC1 and BTB domain-containing protein 1;Chronic lymphocytic leukemia deletion region gene 7 protein;CLL deletion region gene 7 protein;Regulator of chromosome condensation and BTB domain-containing protein 1
Observed Band(KD)：58kD
Background： This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008],
Function：function:May be involved in cell cycle regulation by chromatin remodeling.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 RCC1 repeats.,tissue specificity:Ubiquitously expressed.,
Subcellular Location：Nucleus .
Expression：Ubiquitously expressed (PubMed:11306461, PubMed:27486781). In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level) (PubMed:27486781).
