Target:GP182
Gene Name:GPR182 ADMR
Protein Name:G-protein coupled receptor 182
Human Gene Id:11318
Human Swiss Prot No:O15218
Mouse Swiss Prot No:P43142
Rat Swiss Prot No:P31392
Immunogen:Synthesized peptide derived from human protein . at AA range: 190-270
Specificity:GP182 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):44kD
Background: Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin. [provided by RefSeq, Jul 2008],
Function:caution:Was originally (PubMed:9367907) thought to be a receptor for adrenomedullin.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.,
Subcellular Location:Cell membrane; Multi-pass membrane protein.
Expression:Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.