Target:CLCC1
Gene Name:CLCC1
Protein Name:Chloride channel CLIC-like protein 1
Human Gene Id:23155
Human Swiss Prot No:Q96S66
Mouse Swiss Prot No:Q99LI2
Immunogen:The antiserum was produced against synthesized peptide derived from human CLCC1. AA range:391-440
Specificity:CLCC1 Polyclonal Antibody detects endogenous levels of CLCC1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CLCC1;KIAA0761;MCLC;Chloride channel CLIC-like protein 1;Mid-1-related chloride channel protein 1
Observed Band(KD):62kD
Background:function:Seems to act as a chloride ion channel.,similarity:Belongs to the chloride channel MCLC family.,
Function:function:Seems to act as a chloride ion channel.,similarity:Belongs to the chloride channel MCLC family.,
Subcellular Location:Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Nucleus membrane ; Multi-pass membrane protein . Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes. .
Expression:Expressed in the retina of the eye, with extensive expression in the lamina cribrosa, optic nerve, ganglion cell layer, inner nuclear layer, outer nuclear layer and retinal pigment epithelium.