Target：CITE2

Fields：Mitophagy - animal

Gene Name：CITED2 MRG1

Protein Name：Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG-1) (P35srj)

Human Gene Id：10370

Human Swiss Prot No：Q99967

Mouse Swiss Prot No：O35740

Immunogen：Synthesized peptide derived from human protein . at AA range: 190-270

Specificity：CITE2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：29kD

Background：Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2(CITED2) Homo sapiens The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],

Function：function:Interferes with the binding of transcription factors HIF-1a and STAT2 to p300/CBP.,induction:By hypoxia and deferoxamine.,similarity:Belongs to the CITED family.,subunit:Binds to the p300/CBP CH1 region.,

Subcellular Location：Nucleus . Colocalizes with EP300 in dot-like structures.

Expression： Pancreas,