Target：CIP29

Gene Name：SARNP

Protein Name：SAP domain-containing ribonucleoprotein

Human Gene Id：84324

Human Swiss Prot No：P82979

Mouse Gene Id：66118

Mouse Swiss Prot No：Q9D1J3

Rat Gene Id：362819

Rat Swiss Prot No：Q498U4

Immunogen：The antiserum was produced against synthesized peptide derived from human HCC1. AA range:147-196

Specificity：CIP29 Polyclonal Antibody detects endogenous levels of CIP29 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SARNP;HCC1;HSPC316;SAP domain-containing ribonucleoprotein;Cytokine-induced protein of 29 kDa;Nuclear protein Hcc-1;Proliferation-associated cytokine-inducible protein CIP29

Observed Band(KD)：30kD

Background： This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],

Function：transcription, regulation of transcription, DNA-dependent, regulation of translation, posttranscriptional regulation of gene expression, regulation of cellular protein metabolic process, regulation of transcription, regulation of RNA metabolic process,

Subcellular Location：Nucleus. Nucleus speckle.

Expression：Low expression in spleen, liver, pancreas, testis, thymus, heart, and kidney. Increased levels are seen in hepatocellular carcinoma and pancreatic adenocarcinoma.