Target:CHRAC15
Gene Name:CHRAC1
Protein Name:Chromatin accessibility complex protein 1
Human Gene Id:54108
Human Swiss Prot No:Q9NRG0
Mouse Gene Id:93696
Mouse Swiss Prot No:Q9JKP8
Immunogen:The antiserum was produced against synthesized peptide derived from human CHRC1. AA range:81-130
Specificity:CHRAC15 Polyclonal Antibody detects endogenous levels of CHRAC15 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:CHRAC1;CHRAC15;Chromatin accessibility complex protein 1;CHRAC-1;Chromatin accessibility complex 15 kDa protein;CHRAC-15;HuCHRAC15;DNA polymerase epsilon subunit p15
Molecular Weight(Da):15kD
Background: CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004],
Function:function:Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1.,subunit:Interacts with POLE3. Together with POLE3, ACF1 and ISWI/SNF2H proteins, it forms the ISWI chromatin-remodeling complex, CHRAC.,tissue specificity:Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
Subcellular Location:Nucleus .
Expression:Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.