Target：CHODL

Gene Name：CHODL C21orf68 PRED12 UNQ872/PRO1890

Protein Name：Chondrolectin (Transmembrane protein MT75)

Human Gene Id：140578

Human Swiss Prot No：Q9H9P2

Mouse Swiss Prot No：Q9CXM0

Immunogen：Synthesized peptide derived from human protein . at AA range: 140-220

Specificity：CHODL Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：30kD

Background： This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011],

Function：online information:Chondrolectin,PTM:N-glycosylated.,similarity:Contains 1 C-type lectin domain.,tissue specificity:Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen.,

Subcellular Location：Cytoplasm . Membrane ; Single-pass type I membrane protein .; [Isoform 2]: Endoplasmic reticulum . Endoplasmic reticulum membrane ; Single-pass type I membrane protein .; [Isoform 3]: Cytoplasm .

Expression：Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen. B lymphocytes express isoform 2 only; peripheral blood T lymphocytes express isoform 3 only; granulocytes and monocytes express neither isoform 2 nor isoform 3. During development of T lymphocytes, bone marrow progenitor cells express isoform 2 only; thymocytes at different stages of maturation express predominantly isoform 2 and weakly isoform 3, and mature thymocytes express only isoform 2.