Target：CHAC1

Fields：Glutathione metabolism;Metabolic pathways

Gene Name：CHAC1 BOTCH

Protein Name：Cation transport regulator-like protein 1 (Blocks Notch protein) (Botch)

Human Gene Id：79094

Human Swiss Prot No：Q9BUX1

Mouse Swiss Prot No：Q8R3J5

Rat Swiss Prot No：B3STU3

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：CHAC1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：24kD

Background： This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016],

Function：similarity:Belongs to the chaC family.,

Subcellular Location：Cytoplasm, cytosol . Golgi apparatus, trans-Golgi network .

Expression： Liver,Muscle,