Target：LRRK1

Gene Name：LRRK1

Protein Name：Leucine-rich repeat serine/threonine-protein kinase 1

Human Gene Id：79705

Human Swiss Prot No：Q38SD2

Mouse Swiss Prot No：Q3UHC2

Immunogen：The antiserum was produced against synthesized peptide derived from human LRRK1. AA range:361-410

Specificity：LRRK1 Polyclonal Antibody detects endogenous levels of LRRK1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：LRRK1;KIAA1790;Leucine-rich repeat serine/threonine-protein kinase 1

Molecular Weight(Da)：228kD

Background：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats.,

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats.,

Subcellular Location：Cytoplasm .

Expression： Brain,Cervix,Lung,Macrophage,Pancreas,Skin,Spleen,