Target:GP125
Gene Name:GPR125 UNQ556/PRO1113
Protein Name:Probable G-protein coupled receptor 125
Human Gene Id:166647
Human Swiss Prot No:Q8IWK6
Mouse Swiss Prot No:Q7TT36
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:GP125 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):145kD
Background: This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012],
Function:domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,
Subcellular Location:Membrane ; Multi-pass membrane protein .
Expression: Epithelium,Eye,Liver,