Target：RPA12

Fields：RNA polymerase

Gene Name：ZNRD1 RPA12

Protein Name：DNA-directed RNA polymerase I subunit RPA12 (Zinc ribbon domain-containing protein 1)

Human Gene Id：30834

Human Swiss Prot No：Q9P1U0

Mouse Swiss Prot No：Q791N7

Rat Swiss Prot No：Q6MFY5

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：RPA12 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：13kD

Background： This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Function：function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.,similarity:Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.,similarity:Contains 1 TFIIS-type zinc finger.,subunit:Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.,

Subcellular Location：Nucleus, nucleolus .

Expression： Peripheral blood leukocyte,Skeletal muscle,Skin,